Autoantibodies in pregnancy wastage: perspectives and challenges

  • Dr. Nabaz Fisal Shakir Agha Erbil Polytechnic University, Iraq/Erbil Medical Technical Institute, Erbil/ Iraq
Keywords: Anticardiolipin Antibodies (ACA), Recurrent Abortion, Antinuclear Antibodies (ANA), Intrauterine Fetal Deaths (IUFD)

Abstract

Background: Repeated failure is a serious problematic in which numerous issues show a vital part such as anticardiolipin antibodies (ACA) and antinuclear antibodies (ANA).

Objectives: The goal of this investigation learning was to approximation anticardiolipin (IgG) and antinuclear (IgG) antibodies in patients of recurring unsolved pregnancy damage and intrauterine fatal demises (IUFD).

Methods: One hundred & twenty (120) women were enrolled in this prospective case-controlled study from Maternity Hospital, Erbil City, Iraq. Altogether patients needed absent finished a consistent examination order. They were (60) patients with a past of three & additional attacks of previous abortions and (60) well pregnant. Entirely remained separated for ANA-IgG, ACL-IgG in serum.

Results: It was noted that (19/60, 31.7%) of the patients & (7/60, 11.67%) healthy control were positive for ACL-IgG with a mean concentration of 38±10.3 IU/ml in the patient's group, and 11.6±4.4 IU/ml in the healthy control with highly significant at (p≤0.01). It was shown from the results that (15/60, 25%) of the patients & (6/60, 10%) healthy control were positive for ANA-IgG with a mean concentration of (6.2 ± 0.4) IU/ml in the patients group, and (0.75±0.325) IU/ml in the healthy control with significant at (p≤0.05). The occurrence of both ACL &ANA among the seropositive patients cases were 8/19 (42.11%), whereas 11/19 (57.89%) among the seronegative patient's cases with a significant difference regarding the distribution of ANA in both ACL-positive & ACL-negative cases (P<0.05).

Conclusions: Anticardiolipin and Antinuclear antibodies constitute an important cause of recurrent mid-trimester abortion in Iraqi, women.

Downloads

Download data is not yet available.

Author Biography

Dr. Nabaz Fisal Shakir Agha, Erbil Polytechnic University, Iraq/Erbil Medical Technical Institute, Erbil/ Iraq

Department of Anaesthesia, Erbil Polytechnic University, Iraq/Erbil Medical Technical Institute, Erbil/ Iraq

Published
2021-01-31
How to Cite
Agha, D. N. F. S. (2021). Autoantibodies in pregnancy wastage: perspectives and challenges. International Journal of Medical Studies, 6(1), 32-47. Retrieved from http://ijmsonline.in/index.php/ijms/article/view/164
Issue
Vol 6 No 1 (2021): International Journal of Medical Studies (PRINT ISSN 2542:2766)
Section
Articles

Copyright (c) 2021 Author

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

The Authors retain copyright (full ownership) to their content published in the Journal. We claim no intellectual property rights over the material provided by any User in this Journal. However, by setting pages to be viewed publicly (Open Access), the User agrees to allow others to view and download the relevant content. In addition, Open Access articles might be used by the Provider, or any other third party, for data mining purposes.

The Provider reserves the rights in its sole discretion to refuse or remove any content that is available via the Website.