Abstract
Natural plant-based medications are prized for their efficacy, affordability, and safety. Because of its antibacterial, anti-inflammatory, and restorative qualities, neem (Azadirachta indica) is used extensively in traditional medicine. Excess oil, clogged pores, bacteria, and
inflammation are the main causes of acne vulgaris. By lowering bacteria and calming the skin, herbal components like neem and marigold aid in the fight against acne. Nimbolide and quercetin, two active ingredients in the anti-acne gel, suppress the Cutibacterium acnes bacteria that causes acne, lessen inflammation, and stop recurrence. To guarantee a smooth texture, good spreadability, hydration, and improved absorption, the formulation also contains propylene glycol, glycerine, and Carbopol 940. All things considered, neem-based herbal gel is a promising option for managing acne since it is a gentle, safe, and efficient substitute for synthetic acne treatments.

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